Alström Syndrome

Alström Syndrome is a very rare, hereditary genetic disorder first described by C.H. Alström in Sweden in 1959. Since then, over 500 individuals with Alström Syndrome have been identified in 46 different countries.

Alström Syndrome is progressive. The first sign observed in infants is usually extreme light sensitivity (photophobia) and a movement of the eyes (nystagmus). Another of the first signs may be dilated cardiomyopathy and congestive heart failure in infants under one year of age.

Children rapidly gain weight during their first year and become obese as young children. Later, multiple organ systems in the body can be affected resulting in blindness, hearing impairment, type 2 diabetes, heart failure, liver disease, urological dysfunction, pulmonary fibrosis, and renal failure.

In some cases early diagnosis can lead to a recovery from heart related problems.

For further information on this condition contact Alström Syndrome UK.

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